ICU Admission Diagnoses and ICU Mortality

Ataturk University

Status: Completed

Conditions: Multiple Organ Dysfunction Syndrome; Critical Illness; Acute Respiratory Distress Syndrome (ARDS); Acute Respiratory Failure; Septic Shock; Sepsis

Study type: Observational

Funder types: Other

Identifiers

NCT07369206

ICU-RETRO-2025

2026/1 (Other Identifier)

Details and patient eligibility

About

This retrospective cohort study will evaluate whether syndromic clinical diagnoses present at ICU admission are associated with ICU mortality, independent of physiologic severity scores. Adult patients admitted to a tertiary mixed ICU during 2025 will be assessed.

Full description

Data will be obtained retrospectively from the hospital information system and ICU clinical records. Variables will be recorded based on the first 24 hours after ICU admission. Demographics, admission characteristics, comorbidities, severity scores (APACHE II, SAPS, SOFA), and admission syndromic diagnoses (e.g., sepsis/septic shock, acute respiratory failure, ARDS, MODS) will be collected. The primary outcome is ICU mortality; secondary outcomes include ICU length of stay and ICU discharge disposition.

Enrollment: 1,248 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients (≥18 years) admitted to the ICU between January 1, 2025 and December 31, 2025.
• If a patient has more than one ICU admission during the study period, only the first ICU admission will be included.

Exclusion criteria

• ICU stay <24 hours.
• Missing essential data preventing assessment of the primary outcome (ICU mortality) and/or calculation of severity scores (APACHE II, SAPS, SOFA).

Trial design

1,248 participants in 1 patient group

Adult ICU admissions (2025)

Description:

Adult patients (≥18 years) admitted to a tertiary mixed intensive care unit between January 1, 2025 and December 31, 2025. For patients with multiple ICU admissions, only the first ICU admission will be included. Data will be abstracted retrospectively from electronic medical records and ICU charts; variables will be recorded based on the first 24 hours after ICU admission.