ICU Stay in Patients With Low Ejection Fraction Undergoing Cardiac Revascularization: Comparison of On-pump vs Off-pump Coronary Artery Bypass Grafting

Armed Forces Institute of Cardiology, Pakistan

Status

Completed

Conditions

Cardiac Revascularization

Treatments

Procedure: Coronary Artery Bypass Grafting

Study type

Interventional

Funder types

Other

Identifiers

NCT04639856

AFIC-IERB-SOP-15

Details and patient eligibility

About

Coronary artery bypass graft (CABG) surgery can result in severe postoperative complications, such as renal and pulmonary failure. In about 80% of the cases worldwide, it is currently performed with cardiopulmonary bypass (CPB) with cardiac arrest. Cardiopulmonary bypass leads to a systemic inflammatory response, which may be induced by the contact of circulating blood with artificial surfaces of the extracorporeal circuit.[1] To reduce postoperative complications caused by systemic inflammation, off-pump CABG was reintroduced into clinical practice in the early 1990s. During off-pump surgery, the coronary artery grafts are placed on coronaries of a beating heart, thereby avoiding aortic cross clamping and CPB. [1] There are many studies and debates about the two approaches to cardiac revascularization via CABG. This study aims to answer the question as to difference in the ICU stay of patients with low ejection fraction undergoing cardiac revascularization bet ween off pump and on pump coronary artery bypass grafting and better treatment option shall be adopted in future.

Enrollment

60 patients

Sex

All

Ages

40 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

All patients of either gender between the ages of 40 to 80
Ejection fraction of less than or equal to 35% undergoing CABG.
undergoing CABG.

Exclusion criteria

Patients with ejection fraction of more than 35%
Patients with previous history of cardiac revascularization
Patients with previous history of chronic kidney disease and obstructive sleep apnea.