Identification of Biomarkers for Stress Vulnerability and Resilience

University of Michigan

Status: Enrolling

Conditions: Healthy

Treatments: Behavioral: Maya App

Study type: Interventional

Funder types: Other

Identifiers

NCT05498207

HUM00211856

Details and patient eligibility

About

The purpose of this research study is to understand the biological mechanisms of stress vulnerability (being susceptible to stress) and stress resilience (being able to recover readily from stress), obtain biomarkers (a biological indicator) for stress resilience and to devise strategies for prevention and treatment of stress-related disorders.

Full description

This study will be using the Maya application (app) for the intervention arm, a mobile cognitive behavior therapy (CBT) program for adolescents and young adults experiencing anxiety symptoms. The Maya app, developed at Weill Cornell, teaches cognitive behavioral therapy (CBT) techniques including emotion monitoring, cognitive restructuring, mindfulness, and exposure to help individuals with anxiety.

Enrollment: 500 estimated patients

Sex: All

Ages: 18 to 22 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Incoming Freshmen Students at the University of Michigan

Exclusion criteria

• Suicidal Ideation

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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500 participants in 2 patient groups

No Intervention

No Intervention group

Description:

Participants will complete assessments at baseline, 3 months, 6 months, 9 months and 12 months. (this includes specimen collections, interviews, and surveys). Participants will also be asked to wear a Fitbit for 12 months.

Maya mobile app

Experimental group

Description:

Maya mobile app- CBT based self-help app

Treatment:

Behavioral: Maya App