Identification of Cardiovascular Risk Factors Linked to Renal Failure Progression (Pre-HD)

University Hospital Center (CHU)

Status: Completed

Conditions: Chronic Renal Failure

Study type: Observational

Funder types: Other

Identifiers

NCT00608998

7853 (Other Identifier)

Details and patient eligibility

About

The aim of this study is to appreciate the influence of renal failure progression on vasculopathy (coronary calcifications and left ventricular hypertrophy) and cardiovascular risk factors.

Full description

The aim of this study is to appreciate the relationship between:

• extension of coronary calcifications and chronic renal failure progression
• extension of coronary calcifications and levels of osteoprotegerin (bone disease marker)
• cardiovascular risk factors and coronary calcifications
• cardiovascular risk factors and existence of cardiovascular diseases

Enrollment: 120 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient who has signed the written consent form

• Patient aged > 18 and < 90 years

• Chronic renal failure defined by glomerular filtration rate (GFR)

  • group 1: GFR >90 mL/min with urinary biological abnormalities and GFR comprised between 90 and 60 mL/min
  • group 2: GFR comprised between 60 and 30 mL/min
  • group 3: GFR <30 mL/min but without dialysis therapy

Exclusion criteria

• Chronic renal failure patient requiring dialysis therapy