Identification of Circulating Tumor Cells in the Peripheral Blood of Lung Cancer Patients

Stanford University

Status: Completed

Conditions: Lung Cancer

Treatments: Procedure: phlebotomy

Study type: Observational

Funder types: Other

Identifiers

NCT00568282

IRB-4086

LUN0017 (Other Identifier)

96710 (Other Identifier)

4086

Details and patient eligibility

About

The primary aim of this study is to determine whether we can identify human lung cancer tumor cells in the peripheral blood of lung cancer patients.

Full description

The purpose of this study is to determine whether we can identify lung cancer cells circulating in the peripheral blood of lung cancer patients using cell surface markers found on cancer cells such as CD44 and epithelial specific antigen.

Enrollment: 219 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:Inclusion Criteria:Inclusion Criteria (Cases):

1. Advanced stage (IIIB with malignant effusion or IV) histologically or cytologically confirmed NSCLC
2. Patients must be newly diagnosed (untreated) or have evidence of disease progression at the time of sample collection
3. ability to sign informed consent
4. at least 18 years of age

Inclusion Criteria (Controls):

1. no known prior or active malignancy

2. ability to sign informed consent

3. at least 18 years of age Exclusion Criteria:1. history of any other cancer other than non-melanoma skin cancer within the last 5 years Exclusion Criteria:1. history of any other cancer other than non-melanoma skin cancer within the last 5 years

4. pregnant women