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Identification of Gene Biomarkers in Aging Skin

I

Interleukin Genetics

Status

Completed

Conditions

Skin Aging
Hyperpigmentation

Study type

Observational

Funder types

Industry

Identifiers

NCT00884936
ILI-08-112-USKAG

Details and patient eligibility

About

This study is a blinded, prospective, single-center, clinical study conducted in Japanese female subjects between the ages of 20-75 years. This design uses skin biopsy samples from environmentally exposed areas and unexposed (control) areas within the same subjects to assess the gene expression profile from three different age groups.

Full description

The primary objective of the skin aging study is to investigate changes in gene expression patterns that occur during the aging process.

Enrollment

121 patients

Sex

Female

Ages

20 to 75 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Individuals who are willing to read and sign an informed consent form prior to participating in the study.
  • Individuals who have a temperature of less than or equal to 100 degrees F at the time of biopsy collection.
  • Individuals who had not applied any sunless tanning product on the arms within the past year.
  • Individuals with no prior history of alcoholism (or who consume fewer than 2 to 3 alcoholic beverages per day).
  • Individuals who have not consumed any anti-aging nutritional supplements (multivitamins and multiminerals are acceptable) or aspirin, NSAIDS, or other pain medication in the last 48 hours before biopsy.

Exclusion criteria

  • Male gender
  • Individuals who did not fit the 'inclusion criteria' above.

Trial design

121 participants in 3 patient groups

Group 1
Description:
Young age: 20 to 30 years old
Group 2
Description:
Middle Age: 38 to 48 years old (pre-menopausal only)
Group 3
Description:
Elderly Age: 60 to 75 years old (Post-menopausal only)

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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