Identification of Genomic Changes in Families Having Multiple Members With Tumors

S

St. Joseph's Hospital and Medical Center, Phoenix

Status

Terminated

Conditions

Glioma

Treatments

Other: saliva or blood sample collection

Study type

Observational

Funder types

Other

Identifiers

NCT02386241
14BN108

Details and patient eligibility

About

This study will compare genomic alterations between the parents and the patients with high-grade glioma.

Full description

Genomic changes leading to the formation of brain tumors are slowly being discovered. Despite advances in genomic technology, much analysis is hindered by the lack of control samples that could better delineate genomic alterations leading to disease. The ideal genomic control would be the genetic material of the parents of afflicted individuals. The researchers propose to then compare the genomic material from parents of siblings, both of whom have a diagnosis of a high-grade glioma. Additionally, the researchers will then compare the genomic alterations between the parents and the patients. This analysis will provide an unprecedented insight into genomic level changes that take place between parents and patients that resulted in the formation of a high-grade glioma.

Enrollment

4 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • 18 years or older.
  • Family history of brain tumor in first degree relative

Exclusion criteria

less than 18 years

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2024 Veeva Systems