Identification of Genomic Predictors of Adverse Events After Cardiac Surgery (CABGGenomics)

Mass General Brigham

Status: Enrolling

Conditions: Atrial Fibrillation; Genetic Predisposition to Disease; Myocardial Infarction; Heart Failure; Heart; Dysfunction Postoperative, Cardiac Surgery

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT01258231

2000P001639

5R01HL098601 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

This study aims to identify genetic causes of adverse events after cardiac surgery, such as atrial fibrillation, myocardial infarction, renal dysfunction and heart failure.

Patients undergoing heart surgery at Brigham and Women's Hospital and Texas Heart Institute are eligible to participate.

Full description

This study aims to identify genetic causes of adverse events after cardiac surgery, such as atrial fibrillation, myocardial infarction, renal dysfunction and heart failure. In addition, we also examine blood and urine biomarkers (proteins).

Enrollment: 4,000 estimated patients

Sex: All

Ages: 20 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Undergoing heart surgery
• Willing to provide consent

Exclusion criteria

• Enrolled in a concurrent drug or device trial that precludes concurrent enrollment

Trial design

4,000 participants in 1 patient group

Cardiac surgery

Description:

Adult patients undergoing cardiac surgery