Identification of High Risk People for Colorectal Cancer and Evaluation of a Specific Surveillance System (ISIRECC)

Regional University Hospital Center (CHRU)

Status: Completed

Conditions: Cancer Colorectal

Treatments: Behavioral: Reminder letter

Study type: Interventional

Funder types: Other

Identifiers

NCT02931825

INCa15-SS/ISIRECC

2015-A01607-42 (Other Identifier)

Details and patient eligibility

About

Colorectal cancer is one the most frequent cancer in developed countries. In France, it rank third with 43000 new cases in 2015. French Health Authority recommended colonoscopy screening for people with a high risk for colorectal cancer. But this compliance with colonoscopy is low (20-40%), it is therefore necessary to develop new strategies to improve compliance.

The purpose of this project is to to offer and evaluate the feasibility and the effectiveness of a specific surveillance system for high risk people for colorectal cancer

The project will be divided into 2 phases:

Objectives of the first phase:

• Identify high risk people for colorectal cancer in the department of Indre-et-Loire,
• Fill in as completely as possible their colonoscopic history in the past 5 years,
• Estimate the proportion of high risk people for colorectal cancer in the target population for colorectal cancer screening in Indre-et-Loire (Men and women aged from 50 to 74 years).

Objective of the second phase:

Compare the performed colonoscopy rate of high risk people for colorectal cancer without notion of colonoscopy in the past 58 months following or not (control group) the sending of a letter reminding the importance of compliance with colonoscopy.

Enrollment: 7,101 patients

Sex: All

Ages: 50 to 74 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• residing in Indre et Loire (France)
• with increased risk for colorectal cancer
• who did not perform a colonoscopy in the past 58 months

Exclusion criteria

• none

Trial design

Primary purpose: Screening

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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7,101 participants in 2 patient groups

Reminder letter

Experimental group

Description:

A letter is sent for remind the importance of compliance with colonoscopy AND to encourage people to to consult their general practitioner or gastroenterologist (if they haven't done their follow-up in time).

Treatment:

Behavioral: Reminder letter

Control

No Intervention group

Description:

No intervention (what is done currently)