Identification of Prognostic Factors and Role of Radiotherapy in Patients With Ewing Sarcoma

Istituto Ortopedico Rizzoli

Status: Enrolling

Conditions: Ewing Sarcoma

Treatments: Other: clinical records review

Study type: Observational

Funder types: Other

Identifiers

NCT06243588

ProEwing

Details and patient eligibility

About

assess whether there is a correlation between some factors (age, sex, tumor volume, tumor site, chemotherapy-induced necrosis, radiation and biomarkers) and overall survival (OS) and relapse-free survival (RFS) in patients with Ewing sarcoma.

Identification of reliable prognostic factors could help to identify high-risk patients, which may require a different treatment and follow up.

Enrollment: 400 estimated patients

Sex: All

Ages: 2+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Male and female patients treated at Rizzoli Orthopaedic Institute between 01/01/1991 and 31/12/2021
• Age ≥ 2 years
• Diagnosis of Ewing Sarcoma
• Patients with available clinical and imaging data

Exclusion criteria

• At least one inclusion criterion not met

Trial design

400 participants in 1 patient group

Patients

Description:

patients treated at Rizzoli Institute from 1991 to 2021.

Treatment:

Other: clinical records review