Identification of the Blood Microbiota in Patient Suffering From Myocardial Infraction (FLORINF)

Toulouse University Hospital

Status: Completed

Conditions: Myocardial Infarction; Coronary Disease

Study type: Observational

Funder types: Other

Identifiers

NCT02405468

2013-A00337-38 (Registry Identifier)

12 387 02

Details and patient eligibility

About

The investigators want to compare blood microbiota profile between patients with documented coronary lesions and patients free of coronary disease.

Enrollment: 202 patients

Sex: All

Ages: 35 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Cases : patients who have had a myocardial infarction within one month to one year before the inclusion
• Controls : patients without history of myocardial infarction, free of coronary disease in the view of one of the following tests performed within one year before the inclusion :

Effort test Echocardiographic stress test Myocardial perfusion scintigraphy Coronarography with >= 2 major cardiovascular risk factors:

1. Treated hypertension,
2. Treated dyslipidemia
3. Current smoking
4. Diabetes mellitus

Exclusion criteria

• Infectious disease within one week before the inclusion
• Immunocompromised patients
• Antibiotic treatment within one month before the inclusion
• Chronic viral infection
• Chronic inflammatory intestinal bowel disease
• Renal failure (estimated glomerular filtration rate< 50 ml/min//1.73 m2)
• Pregnancy

Trial design

202 participants in 2 patient groups

case

Description:

patients with a myocardial infarction within one month to one year before the inclusion

control

Description:

patients without history of myocardial infarction, free of coronary disease in the view of one of the following test performed within one year before the inclusion : Effort test Echocardiographic stress test Myocardial perfusion scintigraphy Coronarography with \>= 2 major cardiovascular risk factors : * Treated hypertension * Treated dyslipidemia * Current smoking * Diabetes mellitus