Identification the Expression of Sox2 in Colorectal Cancer Tissues

Sun Yat-sen University

Status: Completed

Conditions: Colorectal Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT01589900

SYSU

Details and patient eligibility

About

Sox2 has been studied in several types of human solid tumors. The investigators found that Sox2 had higher expression level in colorectal cancer and metastatic tissues than normal tissues. So the investigators assumed that whether Sox2 plays an important role in the progression and migration of colon cancer.

Full description

In our study, we examined Sox2 expression in archived human colon cancer tissues and found that its Sox2 expression correlates with reduced patient survival, increased tumor grade and metastasis probability.

Enrollment: 136 patients

Sex: All

Ages: 24 to 79 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of colorectal cancer

Exclusion criteria

• Clinical diagnosis characteristics not exactly described in the patients information