Identifying Changes in Blood (Potential Biomarkers) in Individuals With Drug-Induced Liver Injury
Status
Completed
Conditions
Drug Induced Liver Injury
Details and patient eligibility
About
The purpose of this study is to try to develop new blood tests that may help doctors identify if a drug is hurting a person's liver.
Full description
Our hypothesis is that there are liver-specific particles, called mRNA, that are identifiable in a person's blood sample during liver injury caused by some drugs. The purpose of this study is to try to develop new blood tests that may help doctors identify if a drug is hurting a person's liver, perhaps early in the process before significant injury or illness have occurred.
Enrollment
25 patients
Sex
All
Ages
18 to 80 years old
Volunteers
No Healthy Volunteers
Inclusion and exclusion criteria
Inclusion Criteria:
- ALT > 200 IU/L at presentation to UNC Hospitals
- Drug induced liver injury considered likely by admitting medical staff
Trial design
25 participants in 1 patient group
Acute drug-induced liver injury
Trial contacts and locations
1
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Data sourced from clinicaltrials.gov
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