Identifying Molecular Drivers of Cancer

Avera McKennan Hospital & University Health Center

Status: Completed

Conditions: Advanced Cancer; Tumor; Cancer

Treatments: Genetic: Molecular profile

Study type: Observational

Funder types: Other

Identifiers

NCT02470715

AMEM-2014-CCD001

Details and patient eligibility

About

The primary aim of this study is to identify drivers of cancer by performing comprehensive genetic, proteomic, and metabolomic characterization of patient samples as a basis for understanding the underlying cause of disease.

Full description

This study involves looking at the DNA, RNA, proteins, and metabolites in blood and tissue samples collected from subjects and linking them to their health information. By doing so, researchers hope to discover the underlying molecular causes of human diseases with the hope that this information can be used for the development of diagnostic tests and more effective treatments.

Enrollment: 579 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients diagnoses with cancer but healthy enough to undergo a biopsy procedure
• Between the ages of 18 and 100

Exclusion criteria

• Patients who are pregnant

Trial design

579 participants in 1 patient group

Molecular profile

Description:

Molecular profiled group receiving treatment based on genetics

Treatment:

Genetic: Molecular profile