Identifying Novel Biomarkers in Early Rheumatology Patients

Arthritis Northwest

Status: Unknown

Conditions: Rheumatologic Disorder

Treatments: Other: There is no intervention, but a diagnosis.

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT03843658

R-18002

Details and patient eligibility

About

Patients new to a rheumatology practice will be asked if they want to consent to their blood sample, medical records, and hand/foot x-rays (with sharp scores) for the analysis and correlation with the diagnosis they will receive from the rheumatologist.

Full description

At the end of their first visit new rheumatology patients will be asked for their interest in joining the Inova biomarker study. If yes, the patient will be consented, blood will be drawn for the Inova biomarkers, and x-rays will be sent for sharp scoring. Patients may decline and will not be part of the Inova study. Patients who decline will continue to receive standard of care treatment henceforth.

Patients in the Inova trial will receive a diagnosis from their doctor and are placed into separate cohorts based upon their diagnosis. The Inova biomarker results of each cohort will be cross-correlated with diagnoses, pre-screening tool results. Baseline disease activity and sharp scores will also be correlation variables.

Enrollment: 300 estimated patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Newly referred Arthritis Northwest PLLC
• Age 18 or older

Exclusion criteria

• None.

Trial design

300 participants in 5 patient groups

Rheumatoid Arthritis

Description:

Clinician diagnosed rheumatoid arthritis

Treatment:

Other: There is no intervention, but a diagnosis.

Spondyloarthropathy

Description:

Ankylosing spondylitis and psoriatic arthritis

Treatment:

Other: There is no intervention, but a diagnosis.

Crystalline arthritis

Description:

Gout and Pseudo gout

Treatment:

Other: There is no intervention, but a diagnosis.

Connective Tissue Disease

Description:

Lupus, myositis, scleroderma, and sjogren's

Treatment:

Other: There is no intervention, but a diagnosis.

Non-Inflammatory arthritis

Description:

E.g. Osteoarthritis and Fibromyalgia

Treatment:

Other: There is no intervention, but a diagnosis.