Identifying Patients With Suspicion of Infection in the ED Who Have Low Disease Severity Using MR-proADM - Pilot Study (IDEAL)

BÂ·RÂ·AÂ·HÂ·MÂ·S

Status

Completed

Conditions

Patients Presenting With Suspicion of Infection to the ED

Treatments

Other: MR-proADM guided

Study type

Interventional

Funder types

Industry

Identifiers

NCT03770533

IDEAL pilot

Details and patient eligibility

About

Emergency departments (ED) are becoming increasingly over-crowded, with patients facing prolonged waiting times. Therefore, a safe and rapid assessment that identifies patients with low severity that could be treated as outpatients is essential for improving the workflow within the ED.

The rationale of this IDEAL study is to provide guidance to safely decrease the number of hospital admissions through identification of low risk patients with the biomarker MR-proADM. This will be tested in a pilot study first.

Enrollment

200 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Consecutive patients presenting to the ED with suspicion of infection
Age ≥18 years
Written Informed Consent obtained

Exclusion criteria

Recent major trauma or surgery
End stage renal failure requiring dialysis
Terminal disease and/or very severe medical co-morbidity where death has to be expected in the next 6 months, e.g. due to malignancy, cardiac, renal or hepatic failure
Patients those source of infection always requires hospital admission or never requires hospital admission.
Patients who cannot be discharged for other than medical reasons
Patient participates in any other interventional clinical trial
Patients with active intravenous drug use
Pregnant or lactating women
Patients who are institutionalized by official or judicial order
Dependents of the sponsor, the CRO, the study site or the investigator