Identifying Perceived Barriers and Facilitators Toward a Liver Transplantation Prehabilitation

The University of Alabama at Birmingham

Status: Completed

Conditions: Liver Transplant; Complications

Treatments: Behavioral: Caregiver intervention; Behavioral: Prehabilitation intervention

Study type: Observational

Funder types: Other

Identifiers

NCT04854564

IRB-300007058

Details and patient eligibility

About

The purpose of this study is to formally identify patient and caregiver perceived needs, barriers, and facilitators to inform the development of a home-based multimodal prehabilitation program for potential LT candidates.

Full description

After being informed about the study and potential risks, all participants (patients and caregivers) giving written informed consent will be invited to participate in one of three research activities: interviews (n=10), nominal group technique meetings (n=64), or card-sorting and rating survey (n=40).

Enrollment: 114 patients

Sex: All

Ages: 19 to 74 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Liver transplant (LT) candidates are:

• Adult ESLD patients (age=19-74 years) who are assigned to the LT waitlist
• English-speaking
• No contraindication to moderate intensity physical activities
• Physician clearance for participation in moderate intensity physical activities
• No history of dementia or organic brain syndrome

Caregivers:

• Adult (age≥ 19 years)
• English-speaking
• Provide direct care to LT candidates

Exclusion criteria

• Inability to communicate verbally in English
• Documentation of cognitive deficits

Trial design

114 participants in 2 patient groups

End-stage liver disease (ESLD) patients

Description:

These potential liver transplant candidates are patients with end-stage liver disease (ESLD) who have been assigned to the liver transplant waitlist.

Treatment:

Behavioral: Prehabilitation intervention

Caregivers of potential liver transplant candidates

Description:

They are the primary caregivers for the patients.

Treatment:

Behavioral: Caregiver intervention