Idiopathic Pulmonary Fibrosis Cohort of TCM

Henan University of Traditional Chinese Medicine

Status: Not yet enrolling

Conditions: Idiopathic Pulmonary Fibrosis (IPF)

Treatments: Drug: Traditional Chinese medicine (TCM); Drug: Non-traditional Chinese medicine (non-TCM)

Study type: Observational

Funder types: Other

Identifiers

NCT07162870

Cohort of IPF

Details and patient eligibility

About

This study, based on past registration records, evaluates the clinical efficacy of traditional Chinese medicine in treating IPF in the real world, identifies advantageous populations and clinical targets, and provides references for precision traditional Chinese medicine treatment.

Full description

This study is based on a previously established registry of interstitial lung disease, with traditional Chinese medicine treatment as the exposure factor. A total of at least 1000 IPF patients will be continuously enrolled and followed up for 2 years; it will further observe the pattern of syndromes, disease characteristics, and their interrelationships during disease development, and evaluate the clinical efficacy of traditional Chinese medicine in treating IPF using indicators such as annual acute exacerbation rate and clinical symptoms. Based on the differences in efficacy indicators, it will identify the advantageous population, clarify the clinical efficacy advantage targets, and provide a basis for precision treatment with traditional Chinese medicine.

Enrollment: 1,000 estimated patients

Sex: All

Ages: 40+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Patients diagnosed with IPF;
2. Age ≥ 40 years old;
3. Voluntary participation in this study,And sign the informed consent form.

Exclusion criteria

1. Patients with confusion, dementia, consciousness disorders, and various mental illnesses;
2. Patients who are unable to take care of themselves and have been bedridden for a long time.

Trial design

1,000 participants in 2 patient groups

Traditional Chinese Medicine cohort

Description:

IPF subjects who have continuously used traditional Chinese medicine for standardized treatment for 3 months or more within 1 year, or have accumulated treatment time for 6 months or more, are classified into the traditional Chinese medicine cohort.

Treatment:

Drug: Traditional Chinese medicine (TCM)

Non-Traditional Chinese Medicine cohort

Description:

Other IPF patients who do not meet the inclusion criteria for traditional Chinese medicine cohort, are classified into the non-traditional Chinese medicine cohort.

Treatment:

Drug: Non-traditional Chinese medicine (non-TCM)