Idiopathic Pulmonary Fibrosis (IPF) and the 3 Minutes Sit-to-stand Test (ST2-IPF)

Grenoble Alpes University Hospital Center (CHU)

Status

Completed

Conditions

Idiopathic Pulmonary Fibrosis

Treatments

Diagnostic Test: 3 minutes sit-to-stand test

Study type

Interventional

Funder types

Other

Identifiers

NCT03268915

EssaisCliniques_TCL3-FPI

Details and patient eligibility

About

This study is designed to evaluate the reproductibility and the performance of the 3 minutes sit-to-stand test in patients with idiopathic pulmonary fibrosis.

To do this, the investigators are recruiting 40 patients with idiopathic pulmonary fibrosis in 2 centers (Grenoble university hospital and Lyon university hospital).

Patients had to achieve an effort test on a cycle ergometer. 2 visits are planned in the hospital. During each visit, patients will perform a 3 minutes sit-to-stand test, a 1 minute sit-to-stand test and a 6 minutes walk test. During the second visit, patients will also perform a 3 minutes sit-to-stand test with measurement of oxygen uptake.

The investigators will then analyse the results by comparing numbers of cycle, functional response and symptoms during the 3 minutes sit-to-stand test of the 2 visits. The investigators will also compare the functional response obtained during the 3 minutes sit-to-stand test, the 1 minute sit-to-stand test and the 6 minutes walk test.

Finally, the investigators will compare the maximal values of oxygen uptake, respiration rate and expired volume obtained during the 3 minutes sit-to-stand test to the effort test on cycle ergometer.

Enrollment

35 patients

Sex

All

Ages

18 to 85 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

man or woman aged less than 85 years
patients with Idiopathic Pulmonary Fibrosis without any acute exacerbation during 4 months before the inclusion
Non-opposition to participation in research
Patient with 6 minutes walk test > 200 meters (with or without oxygen therapy)

Exclusion criteria

Patient with reduced locomotor activity, or joint pain that compromises the performance of the tests
Patient with 6 minutes walk test < 200 meters
Patient with an other etiology of pulmonary fibrosis
Other significant pulmonary diseases
Patient with unstable cardiac disease
Patient who may be, according to the investigator's assessment, not cooperating or respecting the obligations inherent in participating to the study.
Opposition to participation in research