IgG-4 Levels in Systemic Sclerosis (SSc-IgG4)

Clalit Health Services

Status: Completed

Conditions: Systemic Sclerosis

Treatments: Diagnostic Test: IgG4 measurement (non-interventional, just obtaining data from medical records)

Study type: Observational

Funder types: Other

Identifiers

NCT04219592

MMC-110-19

Details and patient eligibility

About

This is an observational - non interventional study. The investigators will compare IgG4 levels of 80 healthy donors (from Israel blood bank - MDA) and 80 Systemic Sclerosis patients from Meir Medical Center.

Full description

IgG4 levels will be obtained from medical records of 80 SSc patients between the years 2000-2019. These will be compared to IgG4 levels from sera of 80 healthy donors (from Israel blood-bank - MDA). Correlations between IgG4 levels and the following will be made: age, sex, disease type (limited or diffused SSc), disease duration, medications.

Enrollment: 154 patients

Sex: All

Ages: 18 to 85 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• SSc patients

Exclusion criteria

• other chronic co-morbidities

Trial design

154 participants in 2 patient groups

SSc

Description:

74 SSc patients aged 18 - 85

Treatment:

Diagnostic Test: IgG4 measurement (non-interventional, just obtaining data from medical records)

Healthy controls

Description:

80 Healthy blood-donors aged 18 - 85

Treatment:

Diagnostic Test: IgG4 measurement (non-interventional, just obtaining data from medical records)