IL-38 Evaluation as a Biomarker in Pediatric Asthma

Cairo University (CU)

Status: Completed

Conditions: Bronchial Asthma

Treatments: Diagnostic Test: Il-38 serum level

Study type: Interventional

Funder types: Other

Identifiers

NCT05366491

MS-25-2020

Details and patient eligibility

About

The aim of this study is to investigate the associations between serum IL-38 levels and different variables of asthma in children such as laboratory variables, pulmonary function test results, the diagnosis of asthma, and in correlation with disease severity.

Enrollment: 103 patients

Sex: All

Ages: 6 to 14 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• patients fulfilled the criteria of the Global Initiative for Asthma (GINA)
• Age group:6-14 years

Exclusion criteria

• Malignancy
• Chronic inflammatory diseases

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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103 participants in 2 patient groups

bronchial asthma patients

Active Comparator group

Description:

patients diagnosed with bronchial asthma

Treatment:

Diagnostic Test: Il-38 serum level

healthy controls

Active Comparator group

Description:

healthy subjects with age and sex matched to bronchial asthma patients

Treatment:

Diagnostic Test: Il-38 serum level