IL-6 in Exercise-Induced Anorexia

University of Toronto

Status: Completed

Conditions: Appetitive Behavior; Pediatric Obesity

Treatments: Other: High Intensity Exercise/Ibuprofen

Study type: Interventional

Funder types: Other

Identifiers

NCT03295968

REB32277

Details and patient eligibility

About

This study investigates the effect of high intensity exercise, with and without the inflammation inhibitor, ibuprofen, on plasma levels of IL-6 and other selective biomarkers of inflammation and appetite on food intake and subjective ratings of appetite in normal-weight boys.

Enrollment: 15 patients

Sex: Male

Ages: 13 to 18 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 13-18 yrs, healthy, male

Exclusion criteria

• female, heamatophobia, following a diete, diagnosed with diabetes or other metabolic diseases, scoring ≥11 on an Eating Habit Questionnaire

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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15 participants in 4 patient groups

Water and Rest

No Intervention group

Water and High Intensity Exercise

Experimental group

Treatment:

Other: High Intensity Exercise/Ibuprofen

Ibuprofen and Rest

Experimental group

Treatment:

Other: High Intensity Exercise/Ibuprofen

Ibuprofen and High Intensity Exercise

Experimental group

Treatment:

Other: High Intensity Exercise/Ibuprofen