IL35 Level in Vitiligo

Cairo University (CU)

Status: Not yet enrolling

Conditions: IL35, Vitiligo

Treatments: Diagnostic Test: IL 35 in tissue biopsy

Study type: Observational

Funder types: Other

Identifiers

NCT05980390

IL35 in vitiligo

Details and patient eligibility

About

The aim of this observational study is to evaluate the level of the IL-35 protein in tissue biopsy from patients with active & stable vitiligo.

Enrollment: 84 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with active and stable vitiligo

Exclusion criteria

• Pregnant and lactating women.
• Patients with associated autoimmune or other dermatological diseases e.g., Alopecia areata and lupus erythematous.
• Patients already on both topical and systemic treatment at the time of recruitment.
• Patients on Immunosuppressive drugs.
• Other hypopigmented diseases such as pityriasis alba, tinea versicolor, lichen sclerosis, post inflammatory hypopigmentation and leprosy as excluded by lack of accentuation by wood's light examination.

Trial design

84 participants in 3 patient groups

Active vitiligo

Treatment:

Diagnostic Test: IL 35 in tissue biopsy

Stable vitiligo

Treatment:

Diagnostic Test: IL 35 in tissue biopsy

Normal controls

Treatment:

Diagnostic Test: IL 35 in tissue biopsy