Image-Guided Tumorboost of Bladder Cancer

University of Aarhus

Status and phase: Completed; Phase 2; Phase 1

Conditions: Bladder Neoplasms

Treatments: Radiation: Radiation boost

Study type: Interventional

Funder types: Other

Identifiers

NCT00963404

M-20080210

CIRRO IP 070109 DaBlaCa-1

Details and patient eligibility

About

The purpose of the study is to increase the radiation dose (Boost) to the bladder tumor. The bladder cancer patients included in the study will undergo tumor demarcation. The bladder demarcations will then be the target for an image-guided boost delivered precisely to the expected tumor site.

Enrollment: 19 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Muscle invasive bladder cancer (transitional carcinoma)
• Unifocal
• TNM stage T2a-4a, N0-1, M0
• unfit for radical cystectomy

Exclusion criteria

• Hyperthyroidism
• Multinodular goiter
• Pregnancy
• Breast feeding
• WHO preformance status more than 2
• Iodine allergy
• MRI or CT contrast media allergy
• Bi-lateral hip-prosthesis

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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19 participants in 1 patient group

Tumor-boost

Experimental group

Description:

Image-guided tumorboost of the bladder cancer.

Treatment:

Radiation: Radiation boost