Images in Extracranial Artery Stenosis

National Taiwan University

Status: Unknown

Conditions: Extracranial Atherosclerosis

Study type: Observational

Funder types: Other

Identifiers

NCT00173927

9261701156

NTUH 94N04

Details and patient eligibility

About

The goals of this trial are:

1. To compare the sensitivity and specificity of various tools including Doppler and magnetic resonance imaging (MRI) for diagnosing vertebral artery stenosis and carotid artery stenosis. The positron emission tomography (PET)/MRI fusion imaging will be a promising tool to provide both anatomical and functional imaging for vulnerable plaques.
2. To identify patients at high risk of plaque rupture by image studies, biomedical profile, and gene expression of circulating monocytes.

Enrollment: 100 estimated patients

Sex: All

Ages: 30 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with symptomatic extracranial atherosclerosis who are going to receive angiography and possible intervention.

Exclusion criteria

• Acute systemic illness
• Creatinine > 3 mg/dl
• Unable to tolerate the tests (including MRI and PET/computed tomography [CT] scans)