Imaging of Prostate Cancer Using Two-dimensional MR Spectroscopy and Diffusion Tensor Imaging

University of California Irvine (UCI)

Status: Withdrawn

Conditions: Prostate Lesions

Treatments: Device: magnetic resonance imaging

Study type: Interventional

Funder types: Other

Identifiers

NCT00611065

UCI-HS-2007-5671

Details and patient eligibility

About

The goal is to develop MR imaging techniques to improve delineation of cancer extent, and to improve differential diagnosis between prostate cancer and benign prostate hyperplasia or other benign diseases.

Sex: Male

Ages: 21 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. A male older than 21 years of age and under age of 80,
2. Either a normal healthy volunteer; a patient who has confirmed prostate cancer and decided to receive prostatectomy; or a patient who has persistent elevated PSA higher than 4.0 ng/ml, and with a prior benign biopsy scheduled to receive the second biopsy.

Exclusion criteria

1. Unwilling to give informed consent,
2. Have implanted prosthetic heart valves, pacemaker, neuro-stimulation devices, surgical clips (hemostatic clips) or other metallic implants,
3. Have engaged in occupations or activities which may cause accidental lodging of ferromagnetic materials, or have imbedded metal fragments from military activities,
4. Have received orthodontic work involving ferromagnetic materials,
5. Claustrophobic,
6. Unable to lie down still for 60 minutes.

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)