Imaging of Retinochoroidal Vasculature in Patients Being Assessed for Cardiovascular Disease
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About
This study aims to determine whether changes in retinal vasculature seen on SS-OCTA can be correlated to degree of cardiovascular disease as measured by carotid duplex ultrasonography.
Full description
The study's primary objective is to determine whether measures taken from SS-OCTA, color fundus photography, and retinal exams can correlate with and predict the presence/degree of carotid occlusive disease as determined by carotid duplex ultrasonography by examining the following parameters: retinal vessel caliber, retinal vessel density, retinal vessel perfusion, retinal vessel tortuosity, presence of Hollenhorst or other plaques, and/or areas of ischemia.
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
- Subjects between 18 and 80 years of age.
- No known prior history of retinal disease.
- Able to participate in a clinical eye examination setting.
- Able to consent.
- Subjects receiving standard of care carotid duplex ultrasounds.
Exclusion criteria
- Known ophthalmologic disease (e.g. glaucoma, macular degeneration, ocular injury) other than corrected refractive error.
- Lack of capacity to provide informed consent.
- Subjects younger than 18 years of age or older than 80 years of age.
- History of stroke or acute loss of vision.
- Unable to participate in a clinical eye examination setting.
Trial design
Primary purpose
Allocation
Interventional model
Masking
50 participants in 1 patient group
Trial contacts and locations
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Central trial contact
Arnold Nadel; Clinical Research Office
Data sourced from clinicaltrials.gov
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