Imaging Response to Immunotherapy and Radiation Therapy in Patients With Liver Metastases

Mayo Clinic

Status: Completed

Conditions: Liver Metastases

Treatments: Other: Magnetic Resonance Elastography

Study type: Observational

Funder types: Other

Identifiers

NCT03401814

17-009021

ROR1721 (Other Identifier)

Details and patient eligibility

About

Patients will be imaged with MRE at the time of the RT planning MRI, prior to the induction of RT and immunotherapy. Research imaging will be in addition to standard imaging studies performed at time points consistent with the standard of care (at the time of the RT planning MRI and the first clinical follow-up). An additional MRE exam will be performed at the end of treatment outside the standard of care imaging.

Enrollment: 1 patient

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥ 18 years
• Diagnosis of solid cancers with the presence of one or more liver metastases
• Minimum metastasis diameter ≥ 2 cm
• Planning to receive radiation therapy with immunotherapy
• Willingness to participate in mandatory imaging studies at Mayo Clinic Rochester

Exclusion criteria

• Contraindications for MRI including claustrophobia, pace maker, metal implants, aneurism clips
• Patients who are not able to consent