Imbalances of Regional Pulmonary Ventilation in Patients With Post-acute-COVID-19

Jan-Christoph Lewejohann

Status: Not yet enrolling

Conditions: COVID-19 Pneumonia; Electric Impedance; Post-acute COVID-19 Syndrome

Treatments: Diagnostic Test: additional EIT Measurement

Study type: Observational

Funder types: Other

Identifiers

NCT05238623

KIM-IV-EIT03

Details and patient eligibility

About

Investigation of the correlation of CT-morphological changes of the lung compared to regional ventilation distribution on electrical impedance tomography in patients with post-acute-Covid-19 symptoms.

Full description

Prospective non-interventional, monocentric observational study on imbalances in regional lung ventilation compared to chest CT in post-acute-Covid-19. The aim is to verify the agreement between computerized tomography derived imaging variables and electrical impedance tomography in detecting lung ventilation imbalances. The primary study objective is to match CT morphological changes in regional ventilation in post-acute-COVID-19 patients and/or changes in lung function examination, with changes that can be visualized by electroimpedance tomography.

Enrollment: 50 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• all patients undergoing a Chest CT due to suspected post-acute-Covid-19-syndrome
• >18 years
• informed consent.

Exclusion criteria

• trauma patients and patients with unstable spinal injuries or fractures
• patients with an BMI over 50
• patients with uncontrolled body movements
• Patients with a pacemaker

Trial design

50 participants in 2 patient groups

Control cohort

Description:

lung-healthy volunteers get a EIT measurement

Case cohort

Description:

Patients who receive standard CT and pulmonary function testing also receive electroimpedance tomography measurement

Treatment:

Diagnostic Test: additional EIT Measurement