Immediate Effects of High-intensity Laser Therapy on Knee Joint Position Sense and Knee Muscle Strength in Patients with Knee Osteoarthritis (HILT on KOA)

Mahidol University

Status and phase: Completed; Phase 2

Conditions: Knee Osteoarthritis

Treatments: Device: high-intensity laser therapy; Device: Sham-HILT

Study type: Interventional

Funder types: Other

Identifiers

NCT06632119

MU_CIRB 2024/003.0401 (Other Identifier)

Details and patient eligibility

About

The goal of this clinical trial is to compare whether HILT versus Sham-HILT is effective to reduce pain, improve knee joint position sense, and knee muscle strength.

Participants will undergo a single-session of HILT or Sham-HILT, the measurements of pain, knee joint position sense error, and knee muscle strength will be done at before, immediately after, and 24-hour after the single-session intervention.

Full description

The investigators would like to investigate whether single session of high-intensity laser therapy (HILT) is promising to see the changes in individuals with knee osteoarthritis (KOA)-related knee pain regarding pain intensity, knee joint position sense, and knee muscle strength.

The objectives of this study is to compare pre and post, and between the two groups (HILT versus Sham-HILT) at after interventions regarding pain, knee joint position sense, and knee muscle strength.

Participants will undergo a single-session of HILT or Sham-HILT by an experienced musculoskeletal physical therapist, the measurements of pain, knee joint position sense error, and knee muscle strength will be done at before, immediately after, and 24-hour after the single-session intervention.

Enrollment: 10 patients

Sex: All

Ages: 50+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• knee pain greater than 3 on the Visual Analog Scale (VAS) for more than 3 months
• diagnosed with unilateral knee osteoarthritis by a physician or meeting the American College of Rheumatology Classification Criteria for clinical knee osteoarthritis
• the severity of knee osteoarthritis is classified as grades 0-3 according to the Kellgren-Lawrence (KL) classification
• should not have undergone any specific treatments in the 3 months preceding the recruitment for the study, such as steroid injections.

Exclusion criteria

• any other musculoskeletal problems associated with knee pain
• musculoskeletal problems associated with the hip and ankle joints
• a history of lower limb fracture
• neurological conditions
• contraindications for laser therapy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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10 participants in 2 patient groups, including a placebo group

HILT

Active Comparator group

Description:

high-intensity laser therapy (HILT)

Treatment:

Device: high-intensity laser therapy

Sham_HILT

Placebo Comparator group

Description:

Sham-HILT, the HILT without laser release

Treatment:

Device: Sham-HILT