Immediate Pressor Response to Oral Salt (IPROS)

Mulungushi University

Status: Enrolling

Conditions: High Blood Pressure

Treatments: Other: salt

Study type: Interventional

Funder types: Other

Identifiers

NCT06226636

IPROS

Details and patient eligibility

About

The goal of this study is to establish a diagnostic accuracy of an immediate pressor response to oral salt (IPROS) to identify salt sensitivity of blood pressure (SSBP)

Full description

Participants are given dietary salt and their BP is measured every 10 minutes for 2 hours. IPROS is diagnosed with significant mean arterial pressure increase

For SSBP, participants are put on high salt diet for a week and monitored and low salt week. The Mean arterial pressure difference between high salt and low salt is used to diagnose SSBP

Enrollment: 300 estimated patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Participants will be included if they are males or females, aged 18-65 years.

Exclusion criteria

• Kidney disease, Cardiovascular disease

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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300 participants in 1 patient group

intervention

Experimental group

Description:

intervention given

Treatment:

Other: salt