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Immediate Pressor Response to Oral Salt (IPROS)

M

Mulungushi University

Status

Enrolling

Conditions

High Blood Pressure

Treatments

Other: salt

Study type

Interventional

Funder types

Other

Identifiers

Details and patient eligibility

About

The goal of this study is to establish a diagnostic accuracy of an immediate pressor response to oral salt (IPROS) to identify salt sensitivity of blood pressure (SSBP)

Full description

Participants are given dietary salt and their BP is measured every 10 minutes for 2 hours. IPROS is diagnosed with significant mean arterial pressure increase

For SSBP, participants are put on high salt diet for a week and monitored and low salt week. The Mean arterial pressure difference between high salt and low salt is used to diagnose SSBP

Enrollment

300 estimated patients

Sex

All

Ages

18 to 50 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Participants will be included if they are males or females, aged 18-65 years.

Exclusion criteria

  • Kidney disease, Cardiovascular disease

Trial design

Primary purpose

Diagnostic

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

300 participants in 1 patient group

intervention
Experimental group
Description:
intervention given
Treatment:
Other: salt

Trial contacts and locations

2

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Central trial contact

Sepiso K Masenga, PhD

Data sourced from clinicaltrials.gov

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