Immediate Versus Delayed Loading of Dental Implants in the Anterior Maxilla

Suez Canal University

Status: Completed

Conditions: Dental Implant Loading; Tooth Loss in the Anterior Maxilla; Partial Edentulism of the Maxilla

Treatments: Device: Dental Implant

Study type: Interventional

Funder types: Other

Identifiers

NCT07381283

706/2023

Details and patient eligibility

About

This interventional comparative clinical study was conducted to evaluate and compare the clinical stability and radiographic outcomes of immediate versus delayed loading of dental implants placed in the anterior region of the maxilla. Immediate loading protocols have been shown to improve oral health-related quality of life and patient satisfaction; however, their influence on implant stability and osseointegration remains an area of ongoing investigation.

A total of sixteen dental implants were placed and the participants were randomly allocated into two equal groups using a computer-generated randomization method (www.Randomizer.org). In Group I (control group), eight implants were placed and restored following a delayed loading protocol, with prosthetic loading performed six months after implant placement. In Group II (study group), eight implants were placed and immediately loaded with provisional polymethyl methacrylate (PMMA) restorations. After six months, the provisional restorations were replaced with definitive fixed prostheses.

Preoperative planning of implant placement was performed using cone beam computed tomography (CBCT). Clinical evaluation of implant stability was carried out using the Osstell device, while radiographic assessment of peri-implant bone density and marginal bone changes was performed using standardized indirect digital radiographs. Radiographic evaluations were obtained immediately after implant placement and at six months postoperatively. The clinical and radiographic outcomes of both loading protocols were compared to assess implant stability and osseointegration.

Enrollment: 16 patients

Sex: All

Ages: 20 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adults aged 20-55 years
• Both genders
• Healthy individuals (ASA I) without systemic diseases
• Patients with one or more missing teeth in the anterior maxilla

Exclusion criteria

• Pregnant or lactating women, or females with osteoporosis
• Patients with harmful oral habits such as bruxism or smoking
• Poor oral hygiene
• Gingival or periodontal diseases with severe vertical or horizontal bone loss
• Teeth with periapical or lateral infections or lesions

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

16 participants in 2 patient groups

Delayed Loading Group

Active Comparator group

Description:

Participants in this group received a single dental implant placed in the anterior maxilla. A total of eight implants were placed and restored using a delayed loading protocol, with prosthetic loading performed six months after implant placement.

Treatment:

Device: Dental Implant

Immediate Loading Group

Experimental group

Description:

Participants in this group received a single dental implant placed in the anterior maxilla. A total of eight implants were placed and immediately loaded with provisional restorations. After six months, the provisional restorations were replaced with definitive fixed restorations.

Treatment:

Device: Dental Implant