Immune Benefits of WGP in Elderly

Nestlé

Status

Completed

Conditions

Elderly People

Treatments

Dietary Supplement: Food fibers

Biological: Influenza vaccine (incl. criterion)

Dietary Supplement: Maltodextrin

Study type

Interventional

Funder types

Industry

Identifiers

12.22.NRC

Details and patient eligibility

About

The aim of this research is to assess the immune enhancing property of food fibers in the elderly population.

Enrollment

150 estimated patients

Sex

All

Ages

70+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Male and female elderly volunteers equal or above age of 70
Pre-frail and frail subjects (based on Fried's criteria)
Willing to be vaccinated against influenza and having no contraindication to receive influenza vaccination
Having obtained his/her (or his/her legal representative's) informed consent

Exclusion criteria

Subject with a rapidly deteriorating health status (terminal, severe, or uncontrolled acute/chronic diseases)
Allergy to eggs or influenza vaccine components.
Subject who has received any vaccination in the last 3 months or has previously been vaccinated with the current seasonal influenza vaccine.
Subject who is currently taking, or has taken in the last 4 weeks, or will take immune modulating medication during the study, including steroid, immune suppressive treatment.
Subject who has taken antibiotics in the last 2 months prior to entering the study.
Subject who is consuming regularly prebiotic and/or probiotic supplements, yogurts, and/or other dietary supplements.
Personal or family history of Guillain-Barre syndrome
BMI>35 kg/m2
Subject who has received blood transfusion or had a blood donation during the last 4 weeks prior to the beginning of this study.
Subject who cannot be expected to comply with the study procedures
Currently participating or having participated in another clinical trial during the last 4 weeks prior to the beginning of this study