Immune Characterization of Subcutaneous Adipose Tissue (ATI)

The Washington University

Status

Completed

Conditions

Determine Immune Cell Types in Subcutaneous Adipose Tissue

Treatments

Procedure: Liposuction/lipectomy

Study type

Observational

Funder types

Other

Identifiers

NCT02076087

2013-02113

Details and patient eligibility

About

The overall goal of this proposal is to characterize the immune cell profile of subcutaneous abdominal adipose tissue in lean, overweight, obese and lipedema adults, and to evaluate potential associations between different adipose tissue immune cell types and metabolic profile.

Enrollment

19 patients

Sex

Female

Ages

18 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Women of all races and ethnicity
Age between 18 and 65 years
Body Mass Index (BMI) ≥ 18.5 kg/m²
Weight stable (+/- 3% during the last 2 months before enrollment)
Women already scheduled for above mentioned procedures

Exclusion criteria

Diabetes Mellitus
Recent (<5 years) history of cancer (except in situ ductal breast carcinoma)
Chemotherapy and/or radiation therapy within 4 months before enrollment
Immune system diseases (i.e., autoimmune disorders, acquired immunodeficiency syndrome)
Pregnant or breastfeeding
Take any medication that might affect immune function
Severe organ dysfunction
BMI <18.5 kg/m² or size of each breast is >600 grams, if scheduled for bilateral breast reconstruction