Immune Function of Colorectal Cancer Lymph Nodes

Shanxi Province Cancer Hospital

Status: Not yet enrolling

Conditions: Lymph Node; Colorectal Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT06319404

2022YFC2505700

Details and patient eligibility

About

Lymph nodes are very important immune organs in the human body and play an important role in the physiological and pathological activities of the body, especially in anti-tumor immunity. The role of regional draining lymph nodes in the development of colorectal cancer is still unknown. In this study, the role of lymph nodes in the development of colorectal cancer was investigated through multicenter and multi-omics data.

Enrollment: 500 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Stage I-III colorectal cancer patients undergoing radical surgery
• Complete imaging, pathology and genetics multi-omics data available
• 18-75 years old

Exclusion criteria

• Patients with preoperative neoadjuvant therapy
• Patients with incomplete clinical information
• Patients with other malignant tumors
• Patients with acute infections or untreated chronic infections

Trial design

500 participants in 2 patient groups

negative lymph node

postive lymph node