Immune Response and Cytomegalovirus in Intensive Care Unit (ICU) Patients (2006/25)

Public Assistance-Hospitals of Marseille (AP-HM)

Status: Completed

Conditions: Cytomegalovirus Infection

Treatments: Other: Sampling of blood, phenotypic analysis sub-populations NK by cytometric of stream in multiple markings

Study type: Interventional

Funder types: Other

Identifiers

NCT00699868

2007-A01197-46

Details and patient eligibility

About

This prospective study evaluate the immune status of patients admitted in ICU.CMV remains dormant in the body, but in people with immune deficiency, CMV could reactivate and cause life-threatening pneumonia.

Full description

Candidates will be screened with medical history and blood tests.Then, 2 groups of 20 patients (with or without CMV reactivation) matched for CMV status will be compared for their immune system against CMV.

Enrollment: 29 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age more than 18-year-old
• Informed consent

Exclusion criteria

• minors,
• pregnant or lactating women,
• adults under guardianship,
• immunosuppression at the entrance to resuscitation,
• AIDS

Trial design

29 participants in 2 patient groups

1

Experimental group

Description:

Infection to CMV

Treatment:

Other: Sampling of blood, phenotypic analysis sub-populations NK by cytometric of stream in multiple markings

Other: Sampling of blood, phenotypic analysis sub-populations NK by cytometric of stream in multiple markings

2

Other group

Description:

Group "control CMV"

Treatment:

Other: Sampling of blood, phenotypic analysis sub-populations NK by cytometric of stream in multiple markings

Other: Sampling of blood, phenotypic analysis sub-populations NK by cytometric of stream in multiple markings