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Immune Responses to BCG Vaccination in Malawi and the UK

L

London School of Hygiene and Tropical Medicine

Status and phase

Completed
Phase 2

Conditions

Immunity, Cellular
Hypersensitivity, Delayed Type

Treatments

Biological: BCG

Study type

Interventional

Funder types

Other

Identifiers

Details and patient eligibility

About

BCG vaccination has been found to provide greater protection against TB in the UK than in Malawi. This study compares immune responses in BCG-vaccinated and unvaccinated teenagers and young adults in Malawi and in the UK.

Sex

All

Ages

12 to 25 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • BCG unvaccinated
  • HIV negative
  • Not pregnant
  • Informed Consent

Exclusion criteria

  • HIV positive
  • Pregnant
  • Seriously ill

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

Trial contacts and locations

2

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Data sourced from clinicaltrials.gov

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