Immune Status of Elderly Population Admitted in an Acute Geriatric Unit

P

Public Assistance-Hospitals of Marseille (AP-HM)

Status

Completed

Conditions

Aging

Treatments

Other: Blood test and clinical test

Study type

Interventional

Funder types

Other

Identifiers

NCT00823589
2008 -21

Details and patient eligibility

About

Ageing is associated with vulnerability against infections leading to increased morbidity with risk of death. Innate and adaptive immunities are altered with ageing responsible of deficits in immune response against pathogens and after vaccination, and favouring the elderly vulnerability against a new pathogen with increased bacterial, viral, and fungal infections. If immunity has been widely studied in immunosenescence, there are few prospective, comparative studies with elderly ill patients. Moreover among these studies, pathologies are not well defined. The main objective of our project is to compare the immune state of elderly hospitalised subjects in an acute geriatric unit to the immune state of elderly healthy subjects selected with strict criteria, in order to precise the impact of polypathology and of various pathologies on immunity state.

Enrollment

78 patients

Sex

All

Ages

75+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Subject of 75 or more years old, female or male
  • Subject admitted in the service of short stay gériatrique of the hospital Holy Marguerite, whatever is the motive for admittance
  • Subject not being under supervision(guardianship), nor guardianship
  • Subject benefiting from a benefit system
  • Subject having given its assent of participation or for which the reliable person gave her assent in the case of vulnerable person

Exclusion criteria

  • Subject of less than 75 years old
  • Subject refusing to participate in the study or for whom(which) the reliable person refuses the participation of the subject

Trial design

78 participants in 2 patient groups

pathological group
Experimental group
Description:
pathological group
Treatment:
Other: Blood test and clinical test
healthy aged
Experimental group
Description:
healthy aged
Treatment:
Other: Blood test and clinical test

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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