Immunity After COVID-19 Vaccination (IACOVV)

General Administration of Military Health, Tunisia

Status: Unknown

Conditions: Tunis Military Hospital Staff Vaccinated Against Covid 19

Treatments: Other: Blood sampling (4 per year)

Study type: Observational

Funder types: NETWORK

Identifiers

NCT04924855

UR17DN05-3

Details and patient eligibility

About

The purpose of the research is to evaluate kinetic after vaccination to the COVID-19 coronavirus by measurements of specific and neutralizant antibodies for spike antigenic sequences .

This work will allow us to follow the efficacy and tolerance of the vaccine over a year, to evaluate the antibody profile, their kinetics, the fraction of neutralising antibodies and will also allow us to understand the attitudes to be taken to ensure the best protection for our staff

Full description

Our objective is to follow the hospital staff after vaccination, for this we will include two groups of participants:

G1: vaccinated staff who did not contract the virus (at the date of vaccination) and who had a serology <0 at least at D7 of the date of vaccination dose 1 (known serological value) G2: vaccinated personnel who have contracted the virus with a PCR + and who have positive serology at least at D7 of the date of vaccination (known serological value)

Enrollment: 300 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

RB-approved informed consent, age 18 years or older, male or female, anyone considering COVID-19 vaccination or anyone that has received COVID-19 vaccination.

Subjects can enroll at anytime after vaccination even though they may not have enrolled before vaccination.

Sampling Frequency and timing: Up to 8 total samples in 12 months -

Exclusion criteria

Exclusion: Failure to provide informed consent