Immunity and Nasal Fungal Colonization

Taichung Veterans General Hospital

Status: Completed

Conditions: Colonization, Asymptomatic

Treatments: Other: nasal irrigation

Study type: Observational

Funder types: Other

Identifiers

NCT05231499

CE18237B

Details and patient eligibility

About

Fungal colonization causes opportunistic infection that may manifest when the host's immune status deteriorates. The purpose of this study was to determine the prevalence of fungal colonization in immunocompromised subjects compared to healthy controls.

Enrollment: 58 patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Immunocompromised subjects included those who had known risk factors for fungal infection, including malignant diseases, diabetes, autoimmune disorders, renal or hepatic insufficiency, organ transplantation, or use of immunosuppressants
• Healthy volunteers had neither sinonasal symptoms nor nasal endoscopic inflammation.

Exclusion criteria

• Patients were excluded if they were under 20 years old, were receiving antifungal medication, or were pregnant.

Trial design

58 participants in 2 patient groups

healthy volunteers

immunocompromised subjects

Treatment:

Other: nasal irrigation