Immunogenicity After Two Doses of Meningococcal Outer Membrane Vesicle Vaccine MenBVac

University Hospital, Rouen

Status: Completed

Conditions: Vaccination

Study type: Observational

Funder types: Other

Identifiers

NCT00450554

2007/004/HP

Details and patient eligibility

About

The main objective of the study is to estimate the proportion of children, born between the 01/01/2002 and the 06/23/200, living around Dieppe (cantons Dieppe est, Dieppe Ouest and Offranville), vaccinated by MenBVac, with a serum bactericidal activity against B:14,P1-7,16 clone related to a protection (>= 4), before and after the third MenBvac vaccination.

Enrollment: 236 patients

Sex: All

Ages: 2 to 7 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• children born between 01/01/2000 and 06/23/2005, living in Dieppe-Est, Dieppe-Ouest and Offranville, vaccinated twice by MenBVac
• parental authority(ies)assent

Exclusion criteria

• no parental authority(ies)assent
• no blood sample during the third vaccination
• impossibility of third vaccination