Immunogenicity of COVID-19 Vaccination in Immunocompromised Patients (Auto-COVID-VACC)

Oliver Cornely, MD

Status: Active, not recruiting

Conditions: COVID-19; Adult; Immunocompromised Patients

Study type: Observational

Funder types: Other

Identifiers

NCT05597761

AUTO-COVID-VACC-4943

Details and patient eligibility

About

This multicenter, prospective, non-interventional study aims to evaluate data on humoral and cellular immune response generated within the COVID-19 vaccination standard in immunocompromised patients.

Full description

This study aims to analyze the immune response data generated within the procedures of the standard-of-care COVID-19 vaccination. for immunocompromised patients.

Additional blood will be drawn from the patients at each visit defined within the vaccination standard by using the same vein puncture as used for blood drawings of routine blood samples. Study related blood samples will be used for evaluation of T and B cell response to COVID-19 vaccinations.

For this study, no additional visits or invasive procedures will be performed in addition to the standard interventions.

Enrollment: 49 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient is vaccinated according to the recent version of the COVID-19 vaccination standard for immunocompromised patients.
• Patient is 18 years of age or older at enrollment.
• Written informed consent from patient has been obtained prior to any study related procedures

Exclusion criteria

• Patient is not vaccinated according to the recent version of the COVID-19 vaccination standard. Patient has a positive SARS-CoV-2 antigen test at the first visit.