Immunomodulation Analysis of Radiation Therapy in Pediatric Malignant Brain Tumors

Capital Medical University

Status: Withdrawn

Conditions: Brain Tumor, Pediatric

Study type: Observational

Funder types: Other

Identifiers

NCT04019470

IRPBT

Details and patient eligibility

About

To investigate the effect of radiotherapy on peripheral blood immune cell composition and function in pediatric malignant brain tumor patients.

Sex: All

Ages: 3 to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age from 3 to 18
• To be diagnosed with malignant brain tumors
• To eligible for radiation therapy
• Karnofsky performance status ≥ 70
• No prior radiation exposure
• Informed consent signed for blood sample collection and used for research purpose

Exclusion criteria

• Patients had received radiotherapy previously.
• Patients who had no histological diagnosis
• Patients who do not wish to participate
• Patients with infections