Immunoregulation of Periodontal Disease

Public Assistance-Hospitals of Marseille (AP-HM)

Status: Completed

Conditions: Periodontal Disease

Treatments: Other: Blood sampling

Study type: Interventional

Funder types: Other

Identifiers

NCT00702429

2007-A00632-51

Details and patient eligibility

About

Our design is to test in hospital practice a selection of immune parameters that could assess the pathophysiology and progression of periodontal lesions.

Full description

These parameters will be measured in 25 healthy volunteers and 25 moderate-to severe periodontal disese patients. Phagocytes will be tested phenotypically and functionally, both ex vivo and in vitro.

Enrollment: 23 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Persons appearing spontaneously at the consultation of parodontologie for parodontale disease,
• persons agreeing to undergo a sampling of blood intended for the search

Exclusion criteria

• Presence of a chronic or pointed pathology,
• an age 18-year-old subordinate or 65-year-old superior,
• pregnant women,

Trial design

Primary purpose: Prevention

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

23 participants in 2 patient groups, including a placebo group

1

Experimental group

Description:

Patients achieve of parodontopathies

Treatment:

Other: Blood sampling

Other: Blood sampling

2

Placebo Comparator group

Description:

Patients without parodontales diseases

Treatment:

Other: Blood sampling

Other: Blood sampling