Impact MRSA -PCR on Patient Management

Fondation Hôpital Saint-Joseph

Status: Completed

Conditions: MRSA Bacteremia

Treatments: Diagnostic Test: Polymerase Chain Reaction of Methicillin Resistant Staphyloccus Aureus

Study type: Observational

Funder types: Other

Identifiers

NCT03096405

PCR-SARM

Details and patient eligibility

About

Staphylococcus aureus represents one of the most met germs, with Escherichia coli, during bacteremia. Microbiologist distinguish at aureus S. two profiles of resistance in beta-lactamines: S. aureus sensitive to the methicillin ( SASM) and the S. aureus resistant to the methicillin ( SARM).

With the implementation of the MALDI-TOF, it is now possible to identify the origin responsible of the bacteremia the day of the positivity of the hemoculture ( J0) and to set up a treatment with adapted antibiotic, which, in the case of a sepsis to aureus S., is the vancomycine. Ye it was demonstrated, that the use of the vancomycine on the SASM increased the average duration of stay and a more important rate of relapse.

The PCR SARM was organized in the GHPSJ in 2014. It allows from the day of the positivity of the hemoculture ( J0), to determine the phenotype of resistance of S. aureus.

Enrollment: 50 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Hemoculture positive to Staphylococcus Aureus Methicillin Sensitive

Exclusion criteria

• Positive test to Staphylococcus Aureus Methicillin Sensitive but not hospitalized.