Impact of 5-fraction Stereotactic Partial Breast Irradiation and Whole Breast Irradiation on Cosmetic Outcome and Patient-reported Outcomes in Early-stage Breast Cancer

Yonsei University

Status: Unknown

Conditions: Breast Cancer

Treatments: Radiation: Whole breast irradiation; Radiation: Partial breast irradiation

Study type: Observational

Funder types: Other

Identifiers

NCT03568981

4-2018-0160

Details and patient eligibility

About

This study aim to investigate the effect of 5-fraction stereotactic partial breast irradiation and whole breast irradiation on patient-reported outcomes, cosmetic outcome, and breast tissue fibrosis in early-stage breast cancer.

Enrollment: 200 estimated patients

Sex: Female

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Pathologically confirmed invasive breast carcinoma or ductal carcinoma in situ (DCIS)
• Women who underwent breast-conservating surgery and have a plan to undergoing partial or whole breast irradiation
• Good performance status (ECOG 0-1)

Exclusion criteria

• Recurrent breast cancer
• History of ipsilateral breast irradiation
• Positive resection margin status after breast surgery

Trial design

200 participants in 2 patient groups

Partial Breast Irradiation (PBI)

Description:

Patients receiving 5-fraction stereotactic partial breast irradiation for breast cancer

Treatment:

Radiation: Partial breast irradiation

Whole Breast Irradiation (WBI)

Description:

Patients receiving whole breast irradiation for breast cancer

Treatment:

Radiation: Whole breast irradiation