Impact of a Low Carbohydrate Breakfast on Glucose Control in Type 2 Diabetes

University of British Columbia

Status: Completed

Conditions: Type2 Diabetes

Treatments: Behavioral: Guidelines Breakfast; Behavioral: Low Carbohydrate Breakfast

Study type: Interventional

Funder types: Other

Identifiers

NCT02982330

H16--00377

Details and patient eligibility

About

Large glucose excursions at breakfast are prevalent in type 2 diabetes and can contribute to sustained hyperglycaemia across the day. Lowering consumption of dietary carbohydrate is known to reduce post-meal glucose excursions but it is unknown whether lowering the carbohydrate at breakfast only will impact subsequent post meal glucose excursions throughout the day. The aim of this study is to examine, under free living conditions and using typical dietary patterns, whether eating a breakfast low in carbohydrate can lower daily post-meal glycemia when compared to consuming a low-fat breakfast (per the current diabetes guidelines).

Enrollment: 27 patients

Sex: All

Ages: 30 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Physician-diagnosed Type 2 Diabetes (>6 months)

Exclusion criteria

• Exogenous Insulin
• A1c > 9%
• Cardiovascular, liver, or renal other disease
• Breakfast and meal skippers

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

---

27 participants in 2 patient groups

Low Carbohydrate Breakfast

Experimental group

Description:

Breakfast composition containing \<10% carbohydrate, 75% fat, 15% protein Matched calories

Treatment:

Behavioral: Guidelines Breakfast

Behavioral: Low Carbohydrate Breakfast

Guidelines Breakfast

Active Comparator group

Description:

Breakfast composition containing 55% carbohydrate, 30% fat, 15% protein Matched calories

Treatment:

Behavioral: Guidelines Breakfast

Behavioral: Low Carbohydrate Breakfast