Impact of a Multidisciplinary Consultation Program on Drug Adherence in First Oral Anticancer Treatment (IMPAM)

Centre Hospitalier Universitaire, Amiens

Status: Enrolling

Conditions: Securing Medication Management; Multidisciplinary Consultation Program; Adherence to Oral Anticancer Treatment; Drug Related Toxicity

Treatments: Device: multidisciplinary consultation program

Study type: Observational

Funder types: Other

Identifiers

NCT04797143

PI2021_843_0023

Details and patient eligibility

About

Oncology management has changed dramatically over the last decade with the approval and rapid adoption of newly targeted oral oncology medications. The movement to oral oncology medications has altered the balance of risks and adverse effects (AEs) in the treatment of cancer care. These treatments are associated with a different constellation of AEs and drug interactions. Patients receiving treatment with oral anticancer treatment (OAT) encounter several barriers to adherence, which may include limited access to specialty medications, severe adverse effects, complex medication regimens, and special handling precautions. Medication nonadherence not only reduces the efficacy of drug therapy but also has the potential to increase healthcare expenditures due to disease-related hospitalizations. The purpose of this study is to evaluate the drug adherence in cancer patients, using the medication possession ratio (MPR), before and after the implementation of a multidisciplinary consultation program (MCP), on initiation of OAT.

Enrollment: 300 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• French speaking patients with a newly diagnosed or relapsed cancer, regardless of location and introduction of oral anticancer treatment

Exclusion criteria

• patients treated with hormone therapy only
• Patient with severe psychiatric disorders
• patient who does not speak the French language

Trial design

300 participants in 2 patient groups

control group

Description:

patients in control group receive standard care

intervention group

Description:

intervention group after implementation of a MCP

Treatment:

Device: multidisciplinary consultation program