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Impact of a Personalized Medication Plan on Duration of Treatment With Potent Opioids in Acute Non-cancer Musculoskeletal Pain. (PPPCARE II)

U

University Hospital, Rouen

Status

Enrolling

Conditions

Acute Pathology of the Locomotor System

Treatments

Other: personalized pharmaceutical plan

Study type

Interventional

Funder types

Other

Identifiers

NCT05905146
2020/0426/HP

Details and patient eligibility

About

The aim of this study is to evaluate whether patients who benefit from a personalized pharmaceutical plan (PPP) during their hospitalization, allowing them to be informed and sensitized, are treated for a shorter period of time with strong opioids with a reduced risk of dependence compared to a management according to the usual modalities in the rheumatology services concerned.

Enrollment

200 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patient hospitalized in the rheumatology department
  • Patient with acute pain in the context of a non-cancerous, non-traumatic, high-energy musculoskeletal pathology
  • Patient for whom a prescription of strong opioid derivatives is initiated in rheumatology or patient for whom a prescription of strong opioid derivatives is maintained in rheumatology if the initial prescription has a maximum duration of 30 consecutive days prior to inclusion

Exclusion criteria

  • Patient with cancer or fibromyalgia already diagnosed at inclusion
  • Patient with poor French language skills
  • Taking a strong opioid treatment for more than 30 consecutive days prior to inclusion
  • Person judged by the prescriber or pharmacist as not autonomous for the management of strong opioid treatment
  • Patient already included in the study

Trial design

Primary purpose

Other

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

200 participants in 2 patient groups

interventional group
Experimental group
Description:
benefiting from a multi-professional intervention around the strong opioid treatment with the aim of setting up a personalized pharmaceutical plan
Treatment:
Other: personalized pharmaceutical plan
control group
No Intervention group
Description:
routine management, including medication reconciliation at entry and exit and pharmaceutical analysis of prescriptions

Trial contacts and locations

3

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Central trial contact

Catherine CHENAILLER; Armelle GUIDOTTI

Data sourced from clinicaltrials.gov

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