Impact of Age and BMI on Liver Transplant Outcomes

University of Pittsburgh

Status

Completed

Conditions

Liver Transplant; Complications

Perioperative/Postoperative Complications

Treatments

Procedure: Living Donor

Procedure: Cadaveric

Study type

Observational

Funder types

Other

Identifiers

NCT04853641

STUDY20070432

Details and patient eligibility

About

Prospectively enrolled retrospective chart review and Liver Transplant database review to determine the modifiable and nonmodifiable risk factors specifically relating to Living Donor Liver Transplants. To observe the impact of age and BMI on graft outcomes and whether they impact the intraoperative management, post-operative length of stay, and complications.

Full description

There has been a great deal of research into the characteristics of the donor for organ transplant, with older donors and those with more comorbidities having worse function once the organ is implanted. There has not been a great deal of research in the United States about the recipient's characteristic including age and BMI and the effects on donor organ function. With increasingly expanded criteria for organ recipients especially in the field of living donor organs the investigators plan to show the impact of older age and increased BMI on newly transplanted organs.

Enrollment

700 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

All patients who received a liver transplant at UPMC- Montefiore Hospital Age> 18

Exclusion criteria

Excludes Children (<18 years old) as they do not receive their operation under the same protocols Lost to follow-up prior to 1 year Participation in alternate research protocol that significantly altered the care they received in the perioperative period that may make their inclusion skew results.